Description
Overview:
Lactulose is a synthetic disaccharide used primarily as a laxative to treat constipation and to manage hepatic encephalopathy. It works by drawing water into the bowel, softening stools, and promoting bowel movements.
Formulation:
Lactulose solution typically comes in a clear, viscous liquid form with a slightly sweet taste. It is available in various concentrations, usually around 10-20 grams per 15 mL.
Indications:
– Constipation:Provides gentle relief from occasional constipation.
– Hepatic Encephalopathy: Helps reduce ammonia levels in the blood in patients with liver disease.
Mechanism of Action:
Lactulose is not absorbed in the gastrointestinal tract. Instead, it is fermented by colonic bacteria, producing organic acids that increase osmotic pressure in the intestines, leading to an increase in bowel movements.
Dosage:
The dosage may vary based on the condition being treated and patient response. It is important to follow the healthcare provider’s instructions.
Side Effects:
Common side effects may include:
– Bloating
– Cramping
– Diarrhea
– Flatulence
Serious side effects are rare but can include severe allergic reactions.
Contraindications:
Lactulose should be used cautiously in individuals with:
– Galactose intolerance
– Bowel obstructions
– Certain types of diabetes
Storage:
Store at room temperature, away from moisture and heat. Keep out of reach of children.
Consultation:
Always consult a healthcare provider before starting lactulose, especially if you have underlying health conditions or are taking other medications.
Conclusion:
Lactulose is a safe and effective solution for managing constipation and hepatic encephalopathy when used as directed.
